2657720-07-3
Chemical Structure
ALK5-IN-7
- CAS No.: 2657720-07-3
- Formula:C26H28N4O3S
- Molecular Weight:476.59
IUPAC Name: 2-(4-(7-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)thieno[3,2-b]pyridin-2-yl)pyridin-2-yl)propan-2-ol
InChIKey: GQYMCNXIDCIXDE-UHFFFAOYSA-N
SMILES: OC(C)(C)C1=NC=CC(C2=CC3=NC=CC(OC4=CN(C5CC5)N=C4C6CCOCC6)=C3S2)=C1
Biological Activity: ALK5-IN-7 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-7 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 4)[1].
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ALK5-IN-7 | ALK5-IN-7 is a potent inhibitor of ALK5. Transforming growth factor beta (TGF-β) is a multifunctional cytokine that is involved in regulating cell proliferation, differentiation and apoptosis through complex receptor signaling pathways on the cell surface in an autocrine, paracrine and endocrine manner. ALK5-IN-7 has the potential for the research of TGF-β-related diseases and conditions, including but not limited to tumors, fibrotic diseases, inflammatory diseases, autoimmune diseases, etc (extracted from patent WO2021129621A1, compound 4). | |||||||||||||||||||||
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Keywords
