2659357-95-4
2659357-95-4
Chemical Structure
PARP1-IN-20
- CAS No.: 2659357-95-4
- Formula:C23H19BrN6O3S
- Molecular Weight:539.40
InChIKey: WJWGTIWVSMYTCG-UHFFFAOYSA-N
SMILES: O=C(N)C1=C2C(NC(C3=CC=C(C(N4CCN(C(C5=CSC(Br)=N5)=O)CC4)=O)C=C3)=N2)=CC=C1
Biological Activity: PARP1-IN-20 (compound 19A10) is a potent inhibitor of PARP1, with the IC50 of 4.62 nM and has similar low PARP-Trapping effect compared with Veliparib (HY-10129), IC50 (MDA-MB-436) >100 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PARP1-IN-20 | PARP1-IN-20 (compound 19A10) is a potent inhibitor of PARP1, with the IC50 of 4.62 nM and has similar low PARP-Trapping effect compared with Veliparib (HY-10129), IC50 (MDA-MB-436) >100 μM. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
