2671040-07-4
2671040-07-4
Chemical Structure
LMP7-IN-1
- CAS. Nr.: 2671040-07-4
- Formula:C20H23BN2O6S
- Molecular Weight:430.28
IUPAC Name: ((1R)-2-(benzofuran-3-yl)-1-((((2-(N,S-dimethylsulfonimidoyl)benzyl)oxy)carbonyl)amino)ethyl)boronic acid
InChIKey: YKQVDWHJURNVON-QUZMYUOTSA-N
SMILES: CN=S(C(C=CC=C1)=C1COC(N[C@H](B(O)O)CC2=COC3=CC=CC=C23)=O)(C)=O
Biological Activity: LMP7-IN-1, a Boronic acid derivative, is a potent and selective immunoproteasome subunit LMP7 (β5i) inhibitor with an IC50 of 1.83 nM (WO2021143923A1; compound 20)[1].
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LMP7-IN-1 | LMP7-IN-1, a Boronic acid derivative, is a potent and selective immunoproteasome subunit LMP7 (β5i) inhibitor with an IC50 of 1.83 nM (WO2021143923A1; compound 20). | |||||||||||||||||||||
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