2687265-18-3
Chemical Structure
Anticancer agent 42
- CAS No.: 2687265-18-3
- Formula:C19H16Cl2N2O3
- Molecular Weight:391.25
IUPAC Name: 2,6-dichloro-3-(2-methyl-1H-indol-3-yl)-5-morpholinocyclohexa-2,5-diene-1,4-dione
InChIKey: QGROEQOAPSQCOH-UHFFFAOYSA-N
SMILES: CC1=C(C2=CC=CC=C2N1)C3=C(C(C(Cl)=C(C3=O)N4CCOCC4)=O)Cl
Biological Activity: Anticancer agent 42 (compound 10d) is an orally active anticancer agent, and shows a potent antitumor activity against MDA-MB-231 cell with an IC50 of 0.07 μM. Anticancer agent 42 can exert its anticancer activity by activating apoptotic pathway and p53 expression. Anticancer agent 42 can be used to study metastatic breast cancer[1].
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Anticancer agent 42 | Anticancer agent 42 (compound 10d) is an orally active anticancer agent, and shows a potent antitumor activity against MDA-MB-231 cell with an IC50 of 0.07 μM. Anticancer agent 42 can exert its anticancer activity by activating apoptotic pathway and p53 expression. Anticancer agent 42 can be used to study metastatic breast cancer. | |||||||||||||||||||||
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Keywords
