2709103-20-6
2709103-20-6
Chemical Structure
HDAC6-IN-4
- CAS No.: 2709103-20-6
- Formula:C30H38N2O5
- Molecular Weight:506.63
IUPAC Name: 7-((2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)amino)-N-hydroxyheptanamide
InChIKey: NWHRMDIXMQBLHY-UHFFFAOYSA-N
SMILES: O=C(NO)CCCCCCNCC1=C(OC)C=C(OCC2=C(C)C(C3=CC=CC=C3)=CC=C2)C=C1OC
Biological Activity: HDAC6-IN-4 (C10) is a potent, orally active and highly selective HDAC6 inhibitor with an IC50 value of 23 nM. HDAC6-IN-4 induces cancer cells apoptosis and shows significant antitumor efficacy, without obvious toxicity[1].
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HDAC6-IN-4 | HDAC6-IN-4 (C10) is a potent, orally active and highly selective HDAC6 inhibitor with an IC50 value of 23 nM. HDAC6-IN-4 induces cancer cells apoptosis and shows significant antitumor efficacy, without obvious toxicity. | |||||||||||||||||||||
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