2734167-68-9
Chemical Structure
HPK1-IN-11
- CAS No.: 2734167-68-9
- Formula:C27H25N5O2
- Molecular Weight:451.52
IUPAC Name: 5-(2-methoxyphenyl)-3-(3-methyl-1,2,3,4,4a,5-hexahydrobenzo[b]pyrazino[1,2-d][1,4]oxazin-8-yl)-1H-indazole-6-carbonitrile
InChIKey: WAYLJBYFOHIPAC-UHFFFAOYSA-N
SMILES: N#CC1=CC2=C(C=C1C3=C(OC)C=CC=C3)C(C4=CC(OCC5N6CCN(C5)C)=C6C=C4)=NN2
Biological Activity: HPK1-IN-11 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-11 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 2)[1].
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HPK1-IN-11 | HPK1-IN-11 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-11 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 2). | |||||||||||||||||||||
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Keywords
