2735713-77-4
Chemical Structure
SGC agonist 2
- CAS No.: 2735713-77-4
- Formula:C23H17F2N7O2
- Molecular Weight:461.42
IUPAC Name: (R)-7-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-3,3-dimethyl-2a,8-dihydro-1,5,6,8-tetraazaacenaphthylene-2,4(1H,3H)-dione
InChIKey: QXIITFGLDWZXEU-HNNXBMFYSA-N
SMILES: O=C1[C@]2([H])C3=C(N1)NC(C(C4=C5)=NN(CC6=C(C=CC=C6)F)C4=NC=C5F)=NC3=NC(C2(C)C)=O
Biological Activity: SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031)[1].
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SGC agonist 2 | SGC agonist 2 is a potent agonist of soluble guanylate cyclase (SGC). Soluble guanylate cyclase is a key signal transduction enzyme in the NO-sGC-cGMP signaling pathway. SGC agonist 2 has the potential for the research of cardiovascular disease (heart failure, pulmonary hypertension, angina, myocardial infarction) and fibrotic diseases (renal fibrosis, systemic sclerosis) (extracted from patent WO2021219088A1, compound 031). | |||||||||||||||||||||
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Keywords
