2744249-11-2
2744249-11-2
Chemical Structure
ALV-05-151-02
- CAS No.: 2744249-11-2
- Formula:C27H28F3N5O4
- Molecular Weight:543.54
InChIKey: IAZZVHLSUWYKDS-UHFFFAOYSA-N
SMILES: CN(C)C(CC(NC1=CC=CC(C(F)(F)F)=C1)=O)C2=CC(NC3=CCN(C4C(NC(CC4)=O)=O)C3=O)=CC=C2
Biological Activity: ALV-05-151-02 is a BCL6B zinc finger protein degrader that selectively targets BCL6B over BCL6. ALV-05-151-02 redirects the E3 ubiquitin ligase CRL4CRBN to induce BCL6B degradation and interacts with the H357 residue of BCL6B[1].
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ALV-05-151-02 | ALV-05-151-02 is a BCL6B zinc finger protein degrader that selectively targets BCL6B over BCL6. ALV-05-151-02 redirects the E3 ubiquitin ligase CRL4CRBN to induce BCL6B degradation and interacts with the H357 residue of BCL6B. | |||||||||||||||||||||
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