ALV-05-151-02
ALV-05-151-02 is a BCL6B zinc finger protein degrader that selectively targets BCL6B over BCL6. ALV-05-151-02 redirects the E3 ubiquitin ligase CRL4CRBN to induce BCL6B degradation and interacts with the H357 residue of BCL6B.
For research use only. We do not sell to patients.
- CAS No.: 2744249-11-2
- Formula: C27H28F3N5O4
- Molecular Weight:543.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BCL6B |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2744249-11-2
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Molecular Weight 543.54
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Formula C27H28F3N5O4
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SMILES
CN(C)C(CC(NC1=CC=CC(C(F)(F)F)=C1)=O)C2=CC(NC3=CCN(C4C(NC(CC4)=O)=O)C3=O)=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ALV-05-151-02 Related Classifications
HY-178700 Related Classifications
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Keywords
- ALV-05-151-02
- 2744249-11-2
- BCL6
- B-cell lymphoma 6 protein
- B-cell lymphoma 5 protein (BCL-5)
- Zinc finger and BTB domain-containing protein 27
- Zinc finger protein 51
- U937 cells
- BCL6 R575
- E3 ubiquitin ligase CRL4CRBN
- tertiary amine group
- BCL6B H357 residue
- BCL6B ZF reporter
- BCL6 ZF reporter
- BCL6B zinc finger protein
- Inhibitor
- inhibitor
- inhibit