2752453-58-8
Chemical Structure
Metallo-β-lactamase-IN-7
- CAS No.: 2752453-58-8
- Formula:C12H10N4O2S
- Molecular Weight:274.30
IUPAC Name: 1-((2-aminobenzo[d]thiazol-6-yl)methyl)-1H-imidazole-2-carboxylic acid
InChIKey: AKDVYGWISHGCBY-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CN1CC2=CC=C3N=C(N)SC3=C2)O
Biological Activity: Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC50s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains[1].
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Metallo-β-lactamase-IN-7 | Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC50s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains. | |||||||||||||||||||||
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Keywords