Metallo-β-lactamase-IN-7
Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC50s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains.
For research use only. We do not sell to patients.
- CAS No.: 2752453-58-8
- Formula: C12H10N4O2S
- Molecular Weight:274.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
IC50: 0.019 μM (VIM-2), 13.64 μM (VIM-1), 0.38 μM (VIM-5)[1]
Metallo-β-lactamase-IN-7 (compound 59) (10 μM; 18 - 20 hours) can potentiate Meropenem activity against VIM-2 mediated antibacterial resistance with FIC index values of 0.02[1].
Metallo-β-lactamase-IN-7 (100 μM) potentiates the antibacterial activity of Meropenem against PA W35 with FIC index values of 0.125[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2752453-58-8
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Molecular Weight 274.30
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Formula C12H10N4O2S
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SMILES
O=C(C1=NC=CN1CC2=CC=C3N=C(N)SC3=C2)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Metallo-β-lactamase-IN-7 Related Classifications
HY-143415 Related Classifications
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