2756458-72-5
Chemical Structure
MAT2A-IN-6
- CAS No.: 2756458-72-5
- Formula:C18H13ClF3N3O3
- Molecular Weight:411.76
IUPAC Name: methyl 1-(2-chlorophenyl)-4-(methylamino)-2-oxo-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridine-3-carboxylate
InChIKey: XYANVSKVJNKBPQ-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC)C2=C(N(C3=CC=CC=C3Cl)C1=O)N=C(C(F)(F)F)C=C2)OC
Biological Activity: MAT2A-IN-6 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 18)[1].
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MAT2A-IN-6 | MAT2A-IN-6 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 18). | |||||||||||||||||||||
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