2758905-51-8
Chemical Structure
Anticancer agent 133
- CAS No.: 2758905-51-8
- Formula:C24H19Cl3N5ORh
- Molecular Weight:602.71
InChIKey: QYLZDQTYVGUGAZ-UHFFFAOYSA-K
SMILES: Cl[Rh]12(Cl)([N]#CC)[N]3=C(C(N2C4=CC=CC=C4)=O)C(Cl)=CC=C3N5C(C6=CC=CC=C6)=CC(C)=[N]51
Biological Activity: Anticancer agent 133 (compound Rh2) is an anti-cancer agent with cytotoxic and antimetastatic activities. Anticancer agent 133 induces cell cycle arrest, apoptosis, and autophagy. Anticancer agent 133 also inhibits cell metastasis via suppression of EGFR expression mediated by FAK-regulated integrin β1[1].
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Anticancer agent 133 | Anticancer agent 133 (compound Rh2) is an anti-cancer agent with cytotoxic and antimetastatic activities. Anticancer agent 133 induces cell cycle arrest, apoptosis, and autophagy. Anticancer agent 133 also inhibits cell metastasis via suppression of EGFR expression mediated by FAK-regulated integrin β1. | |||||||||||||||||||||
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Keywords