2761259-09-8
2761259-09-8
Chemical Structure
PDGFRα/FLT3-ITD-IN-2
- CAS No.: 2761259-09-8
- Formula:C28H41N9O
- Molecular Weight:519.68
IUPAC Name: 3,4,5,6-tetrabromophthalic acid
InChIKey: LEPCIRKHMJHAPC-HZCBDIJESA-N
SMILES: NCCCCNC(C1=CC=C(C=C1)CNC2=NC(N[C@H]3CC[C@@H](CC3)N)=NC4=C2N=CN4C5CCCC5)=O
Biological Activity: PDGFRα/FLT3-ITD-IN-2 (Compound 13d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 20 and 1.654 μM, respectively. PDGFRα/FLT3-ITD-IN-2 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
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PDGFRα/FLT3-ITD-IN-2 | PDGFRα/FLT3-ITD-IN-2 (Compound 13d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of more than 20 and 1.654 μM, respectively. PDGFRα/FLT3-ITD-IN-2 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia. | |||||||||||||||||||||
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