2764746-08-7
Chemical Structure
(R,R,S)-AHPC
Synonym(s): (R,R,S)-VH032-NH2;(R,R,S)-VHL ligand 1
- CAS No.: 2764746-08-7
- Formula:C22H31ClN4O3S
- Molecular Weight:467.02
IUPAC Name: (2R,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
InChIKey: JYRTWGCWUBURGU-KXPMFKKKSA-N
SMILES: CC1=C(SC=N1)C(C=C2)=CC=C2CNC([C@@H]3N(C[C@@H](C3)O)C([C@@H](N)C(C)(C)C)=O)=O.Cl
Biological Activity: (R,R,S)-AHPC ((R,R,S)-VH032-NH2) is a VHL ligand based on (S,R,S)-AHPC that recruits von Hippel-Lindau (VHL) protein. (R,R,S)-AHPC can be linked to a target protein ligand via a linker to form a PROTACs.
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(R,R,S)-AHPC | (R,R,S)-AHPC ((R,R,S)-VH032-NH2) is a VHL ligand based on (S,R,S)-AHPC that recruits von Hippel-Lindau (VHL) protein. (R,R,S)-AHPC can be linked to a target protein ligand via a linker to form a PROTACs. | |||||||||||||||||||||
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Keywords
