(R,R,S)-AHPC
(R,R,S)-AHPC ((R,R,S)-VH032-NH2) is a VHL ligand based on (S,R,S)-AHPC that recruits von Hippel-Lindau (VHL) protein. (R,R,S)-AHPC can be linked to a target protein ligand via a linker to form a PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 2764746-08-7
- Formula: C22H31ClN4O3S
- Molecular Weight:467.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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VHL |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2764746-08-7
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Molecular Weight 467.02
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Formula C22H31ClN4O3S
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SMILES
CC1=C(SC=N1)C(C=C2)=CC=C2CNC([C@@H]3N(C[C@@H](C3)O)C([C@@H](N)C(C)(C)C)=O)=O.Cl
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Synonyms
(R,R,S)-VH032-NH2; (R,R,S)-VHL ligand 1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)