2765046-07-7
2765046-07-7
Chemical Structure
FGFR4-IN-7
- CAS No.: 2765046-07-7
- Formula:C26H25Cl2N5O3
- Molecular Weight:526.41
IUPAC Name: (E)-2-cyano-3-cyclopropyl-N-(3-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)propyl)acrylamide
InChIKey: CZQWRNOUWJSJHW-LICLKQGHSA-N
SMILES: COC1=CC(OC)=C(C(C2=CC3=CN=C(N=C3C=C2)NCCCNC(/C(C#N)=C/C4CC4)=O)=C1Cl)Cl
Biological Activity: FGFR4-IN-7 (Compound C3) is a covalent reversible FGFR4 inhibitor with an IC50 value of 0.42 μM. FGFR4-IN-7 induces apoptosis via the FGFR4 signaling pathway blockage. FGFR4-IN-7 can be used for the research of hepatocellular carcinoma (HCC)[1].
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FGFR4-IN-7 | FGFR4-IN-7 (Compound C3) is a covalent reversible FGFR4 inhibitor with an IC50 value of 0.42 μM. FGFR4-IN-7 induces apoptosis via the FGFR4 signaling pathway blockage. FGFR4-IN-7 can be used for the research of hepatocellular carcinoma (HCC). | |||||||||||||||||||||
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