2765183-10-4
2765183-10-4
Chemical Structure
TK-642
- CAS No.: 2765183-10-4
- Formula:C17H20ClN7S
- Molecular Weight:389.91
InChIKey: DLWCPNNOJKLNDF-UHFFFAOYSA-N
SMILES: NCC1(C)CCN(C2=CN=C3C(NN=C3SC4=C(Cl)C=NC=C4)=N2)CC1
Biological Activity: TK-642 is a highly active, selective, orally activity SHP2 inhibitor based on pyrazole and pyrazine (IC50=2.7 nmol/L). TK-642 can effectively inhibit the proliferation of esophageal carcinoma cells and induce cell apoptosis. TK-642 can be used in the study of esophageal cancer[1].
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TK-642 | TK-642 is a highly active, selective, orally activity SHP2 inhibitor based on pyrazole and pyrazine (IC50=2.7 nmol/L). TK-642 can effectively inhibit the proliferation of esophageal carcinoma cells and induce cell apoptosis. TK-642 can be used in the study of esophageal cancer. | |||||||||||||||||||||
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