2765433-05-2
2765433-05-2
Chemical Structure
MAT-POS-e194df51-1
- CAS No.: 2765433-05-2
- Formula:C24H21ClN4O3S
- Molecular Weight:480.97
InChIKey: YAYDSAMHSQCKIM-OAQYLSRUSA-N
SMILES: N#CC1(CC1)CS(=O)(N2CC3=C([C@@H](C2)C(NC4=C5C=CC=CC5=CN=C4)=O)C=C(C=C3)Cl)=O
Biological Activity: MAT-POS-e194df51-1 is an orally active, non-covalent and non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 value of 37nM. MAT-POS-e194df51-1 is cytotoxic with EC50 values of 64 nM and 126 nM in A549-ACE2-TMPRSS2 cells and HeLa -ACE2 cells, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MAT-POS-e194df51-1 | 98.45% | MAT-POS-e194df51-1 is an orally active, non-covalent and non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 value of 37nM. MAT-POS-e194df51-1 is cytotoxic with EC50 values of 64 nM and 126 nM in A549-ACE2-TMPRSS2 cells and HeLa -ACE2 cells, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
