2766385-56-0
2766385-56-0
Chemical Structure
TMX-4116
- CAS No.: 2766385-56-0
- Formula:C17H19N5O4S
- Molecular Weight:389.43
IUPAC Name: 3-(4-(4-methoxy-5-(pyrrolidine-1-carbonyl)thiophen-3-yl)-1H-1,2,3-triazol-1-yl)piperidine-2,6-dione
InChIKey: OOIINFBRWZQRRM-UHFFFAOYSA-N
SMILES: O=C(C(N1N=NC(C2=CSC(C(N3CCCC3)=O)=C2OC)=C1)CC4)NC4=O
Biological Activity: TMX-4116 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TMX-4116 | 99.76% | TMX-4116 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma. | ||||||||||||||||||||
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