2767987-38-0
2767987-38-0
Chemical Structure
ZNL-0056
- CAS No.: 2767987-38-0
- Formula:C25H27N5O3S
- Molecular Weight:477.58
InChIKey: DZTGCJZKRUDIGP-GOSISDBHSA-N
SMILES: O=C(C1=CSC(NC(C=C)=O)=C1)NC2=NC3=CC=CC(C)=C3N2[C@H]4CN(CCCC4)C(C=C)=O
Biological Activity: ZNL-0056 is an orally active ATP-competitive inhibitor that targets both the Cys797 and Cys775 in the ATP binding site of EGFR. ZNL-0056 selectively inhibits EGFR and its downstream signaling in H3255 cells. ZNL-0056 can be used for the research of cancer[1].
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ZNL-0056 | ZNL-0056 is an orally active ATP-competitive inhibitor that targets both the Cys797 and Cys775 in the ATP binding site of EGFR. ZNL-0056 selectively inhibits EGFR and its downstream signaling in H3255 cells. ZNL-0056 can be used for the research of cancer. | |||||||||||||||||||||
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