2770246-86-9
2770246-86-9
Chemical Structure
HSD17B13-IN-57
- CAS No.: 2770246-86-9
- Formula:C24H16Cl2F3N3O5
- Molecular Weight:554.30
InChIKey: BSIBEGKVMGTRRY-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=CC3=C2C(N(CC4=C(OC(F)(F)F)C=CC=C4)C(N3C)=O)=O
Biological Activity: HSD17B13-IN-57 (Compound 93) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-57 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-57 | HSD17B13-IN-57 (Compound 93) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-57 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
