2770858-49-4
Chemical Structure
Biological Activity: Lunsekimig (SAR443765) is a TSLP/IL-13 inhibitor. Lunsekimig blocks the functional activities of TSLP and IL-13, suppresses type 2 inflammation and improves pulmonary function. Lunsekimig is applicable to research related to asthma[1][2].
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Lunsekimig | 99.00% | Lunsekimig (SAR443765) is a TSLP/IL-13 inhibitor. Lunsekimig blocks the functional activities of TSLP and IL-13, suppresses type 2 inflammation and improves pulmonary function. Lunsekimig is applicable to research related to asthma. | ||||||||||||||||||||
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- [1]. Deiteren A, et al. A first-in-human, single and multiple dose study of lunsekimig, a novel anti-TSLP/anti-IL-13 NANOBODY® compound, in healthy volunteers. Clinical and translational science. 2024 Jun;17(6):e13864. [Content Brief]
- [2]. Deiteren A, et al. A proof-of-mechanism trial in asthma with lunsekimig, a bispecific NANOBODY molecule. The European respiratory journal. 2025 Apr;65(4):2401461. [Content Brief]
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