2812352-99-9
Chemical Structure
MALT1-IN-11
- CAS No.: 2812352-99-9
- Formula:C20H16F4N8O
- Molecular Weight:460.39
IUPAC Name: (S)-N-(6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl)-2-fluoro-8,8-dimethyl-7,8-dihydro-6H-cyclopenta[e]pyrazolo[1,5-a]pyrimidine-6-carboxamide
InChIKey: MAVWHMAQDMDCPQ-NSHDSACASA-N
SMILES: CC1(C2=C(C=NC3=CC(F)=NN32)[C@H](C1)C(NC4=CN=C(N5N=CC=N5)C(C(F)(F)F)=C4)=O)C
Biological Activity: MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1].
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MALT1-IN-11 | MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders. | |||||||||||||||||||||
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Keywords
