MALT1-IN-11
MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders.
For research use only. We do not sell to patients.
- CAS No.: 2812352-99-9
- Formula: C20H16F4N8O
- Molecular Weight:460.39
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
MALT1-IN-11 (Example 151, 24 h) inhibits IL10 secretion in OCI-LY10 cell with an IC50 of 10-100 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 2812352-99-9
-
Molecular Weight 460.39
-
Formula C20H16F4N8O
-
SMILES
CC1(C2=C(C=NC3=CC(F)=NN32)[C@H](C1)C(NC4=CN=C(N5N=CC=N5)C(C(F)(F)F)=C4)=O)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MALT1-IN-11 Related Classifications
HY-150232 Related Classifications
Powered by Bioz