2820126-49-4
2820126-49-4
Chemical Structure
DHFR-IN-4
- CAS No.: 2820126-49-4
- Formula:C18H21N5O2S
- Molecular Weight:371.46
IUPAC Name: 6-(morpholinomethyl)-5-(p-tolyl)imidazo[2,1-b]thiazole-3-carbohydrazide
InChIKey: MSIRVCGEZTUEOG-UHFFFAOYSA-N
SMILES: O=C(C1=CSC2=NC(CN3CCOCC3)=C(C4=CC=C(C)C=C4)N21)NN
Biological Activity: DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with an IC50 value of 123 nM. DHFR-IN-4 also has inhibitory activity against EGFR and HER2 with IC50s of 246 nM and 357 nM, respectively. DHFR-IN-4 has remarkable broad spectrum cytotoxic potency against cancer cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DHFR-IN-4 | 99.19% | DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with an IC50 value of 123 nM. DHFR-IN-4 also has inhibitory activity against EGFR and HER2 with IC50s of 246 nM and 357 nM, respectively. DHFR-IN-4 has remarkable broad spectrum cytotoxic potency against cancer cells. | ||||||||||||||||||||
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References
Keywords
