2833706-13-9
2833706-13-9
Chemical Structure
FGFR3-IN-4
- CAS No.: 2833706-13-9
- Formula:C26H24ClN7O
- Molecular Weight:485.97
IUPAC Name: (R)-4-(4-(3-chloro-4-(1-(2-cyanophenyl)ethoxy)pyrazolo[1,5-a]pyridin-6-yl)-5-methyl-1H-pyrazol-1-yl)piperidine-1-carbonitrile
InChIKey: KBCMVZNCBWKZQE-GOSISDBHSA-N
SMILES: C[C@H](C1=C(C=CC=C1)C#N)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(Cl)C=N5
Biological Activity: FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
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FGFR3-IN-4 | FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1. | |||||||||||||||||||||
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References
Keywords
