2839515-65-8
2839515-65-8
Chemical Structure
Zandelisib hydrochloride
Synonym(s): ME-401 hydrochloride; PWT-143 hydrochloride
- CAS. Nr.: 2839515-65-8
- Formula:C31H38F2N8O.xHCl
- Molecular Weight:576.68 (free base)
SMILES: CN1CCC(C2=CC=CC=C2CC(NC3=NC(N4C5=CC=CC=C5N=C4C(F)F)=NC(N6CCOCC6)=N3)(C)C)CC1.Cl.[x]
Biological Activity: Zandelisib (ME-401) hydrochloride is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib hydrochloride can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib hydrochloride can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma[1].
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Zandelisib hydrochloride | Zandelisib (ME-401) hydrochloride is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib hydrochloride can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib hydrochloride can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma. | |||||||||||||||||||||
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