2849338-46-9
2849338-46-9
Chemical Structure
HSD17B13-IN-99
- CAS No.: 2849338-46-9
- Formula:C24H19F3N4O4
- Molecular Weight:484.43
InChIKey: KKOGXQFCXJSUCW-UHFFFAOYSA-N
SMILES: OC1=C(C(F)(F)F)N=C(C(NC2=CC=CC(N=CN3CCC4=CC=CC=C4OC)=C2C3=O)=O)C=C1
Biological Activity: HSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-99 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-99 | HSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-99 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
