2850253-95-9
2850253-95-9
Chemical Structure
CDK8-IN-9
- CAS No.: 2850253-95-9
- Formula:C24H20F3N3O
- Molecular Weight:423.43
IUPAC Name: 3-(3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)-N-(4-methyl-3-(trifluoromethyl)phenyl)propanamide
InChIKey: MCCKGEPZYYKAEX-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C)C(C(F)(F)F)=C1)CCC2=CC=CC(C3=CN=C(NC=C4)C4=C3)=C2
Biological Activity: CDK8-IN-9 (compound 22) is a potent type II CDK8 inhibitor with an IC50 value of 48.6 nM. CDK8-IN-9 can inhibit tumor growth and is used in colorectal cancer studies[1].
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CDK8-IN-9 | CDK8-IN-9 (compound 22) is a potent type II CDK8 inhibitor with an IC50 value of 48.6 nM. CDK8-IN-9 can inhibit tumor growth and is used in colorectal cancer studies. | |||||||||||||||||||||
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References
Keywords
