2858812-88-9
2858812-88-9
Chemical Structure
LEB-03-153
- CAS No.: 2858812-88-9
- Formula:C40H44N10O6
- Molecular Weight:760.84
IUPAC Name: (6R,7R)-3-((carbamoyloxy)methyl)-7-((Z)-2-(furan-2-yl)-2-((methoxy-13C-d3)imino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: JLFBDEYLDFIMDA-UHFFFAOYSA-N
SMILES: C=CCN1C(C2=C(N1C3=NC(C(C)(O)C)=CC=C3)N=C(N=C2)NC4=CC=C(C=C4)N5CCN(CC5)C(CCC6=CC=C(O6)N7CCN(CC7=O)C(C=C)=O)=O)=O
Biological Activity: LEB-03-153 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through no linker[1].
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LEB-03-153 | LEB-03-153 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through no linker. | |||||||||||||||||||||
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References
Keywords
