2866140-40-9
2866140-40-9
Chemical Structure
RmlA-IN-2
- CAS No.: 2866140-40-9
- Formula:C22H26BrN5O4S
- Molecular Weight:536.44
IUPAC Name: N-(6-((4-aminobutyl)amino)-1-(4-bromobenzyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-methylbenzenesulfonamide
InChIKey: IAVMPVZGAIJJDC-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC=C1)(N(C2=C(NCCCCN)N(CC3=CC=C(Br)C=C3)C(NC2=O)=O)C)=O
Biological Activity: RmlA-IN-2 (Compound 1d) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.303 μM. RmlA-IN-2 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-2 affects bacterial cell wall permeability[1].
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RmlA-IN-2 | RmlA-IN-2 (Compound 1d) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.303 μM. RmlA-IN-2 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-2 affects bacterial cell wall permeability. | |||||||||||||||||||||
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References
Keywords
