2869183-63-9
2869183-63-9
Chemical Structure
Z6466608628
- CAS No.: 2869183-63-9
- Formula:C23H24N4O3
- Molecular Weight:404.46
IUPAC Name: 3-(1-oxo-4-(4-(piperazin-1-yl)phenyl)isoindolin-2-yl)piperidine-2,6-dione
InChIKey: KMGAXUJZURDCDU-UHFFFAOYSA-N
SMILES: O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=CC=C3C4=CC=C(C=C4)N5CCNCC5
Biological Activity: Z6466608628 is a selective PPIL4 molecular glue degrader with human PPIL4 EC50 values of 0.34 µM. Z6466608628 functionally recruits PPIL4 to CRBN, induces CRL4CRBN-mediated ubiquitylation and degradation of PPIL4. Z6466608628 can be used for the research of intracranial aneurysms[1].
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Z6466608628 | Z6466608628 is a selective PPIL4 molecular glue degrader with human PPIL4 EC50 values of 0.34 µM. Z6466608628 functionally recruits PPIL4 to CRBN, induces CRL4CRBN-mediated ubiquitylation and degradation of PPIL4. Z6466608628 can be used for the research of intracranial aneurysms. | |||||||||||||||||||||
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References
Keywords
