287173-08-4
Chemical Structure
CEB-1604
- CAS No.: 287173-08-4
- Formula:C18H25N
- Molecular Weight:255.40
IUPAC Name: ((1R,3S,5r,7r)-2-(m-tolyl)adamantan-2-yl)methanamine
InChIKey: UOQAPRSNEKTPDA-SSAZZLEASA-N
SMILES: NCC1(C2=CC(C)=CC=C2)[C@H]3C[C@H](C4)C[C@@H]1C[C@H]4C3
Biological Activity: CEB-1604 is an NMDA receptor antagonist. CEB-1604 inhibits NMDA-induced currents in oocytes transfected with NMDA receptor isoforms (NR1/NR2A, NR1/NR2B, NR1/NR2C, NR1/NR2D) with IC50 values ranging from 5 to 12 μM. CEB-1604 abolishes NMDA-dependent epileptiform discharges in rat cortical wedge preparations and reduces the depolarizing effects of NMDA. CEB-1604 can be used in the research field of neurological damage diseases[1].
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CEB-1604 | CEB-1604 is an NMDA receptor antagonist. CEB-1604 inhibits NMDA-induced currents in oocytes transfected with NMDA receptor isoforms (NR1/NR2A, NR1/NR2B, NR1/NR2C, NR1/NR2D) with IC50 values ranging from 5 to 12 μM. CEB-1604 abolishes NMDA-dependent epileptiform discharges in rat cortical wedge preparations and reduces the depolarizing effects of NMDA. CEB-1604 can be used in the research field of neurological damage diseases. | |||||||||||||||||||||
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Keywords
