2877694-62-5
2877694-62-5
Chemical Structure
RWT9996
- CAS No.: 2877694-62-5
- Formula:C17H12FN3O2S
- Molecular Weight:341.36
InChIKey: CIEHJRVOVGTTOK-UHFFFAOYSA-N
SMILES: FC1=C(NS(C2=CNC(C3=CC=CC=C3)=C2)(=O)=O)C=CC(C#N)=C1
Biological Activity: RWT9996 is a balanced GPR17 antagonist. RWT9996 has an inhibitory effect on G protein activation and β-arrestin-2 recruitment induced by MDL-29951. RWT9996 inhibits the phosphorylation of ERK/CREB and the accumulation of inositol phosphate (b IP1) induced by MDL-29951. RWT9996 can be used for the study of neurological diseases[1].
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RWT9996 | RWT9996 is a balanced GPR17 antagonist. RWT9996 has an inhibitory effect on G protein activation and β-arrestin-2 recruitment induced by MDL-29951. RWT9996 inhibits the phosphorylation of ERK/CREB and the accumulation of inositol phosphate (b IP1) induced by MDL-29951. RWT9996 can be used for the study of neurological diseases. | |||||||||||||||||||||
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References
Keywords
