2879250-73-2
2879250-73-2
Chemical Structure
WIZ degrader 5
- CAS. Nr.: 2879250-73-2
- Formula:C21H27N3O4
- Molecular Weight:385.46
InChIKey: IHBGNCYMSRWSLK-NHSXVPOTSA-N
SMILES: O=C1N(C2C(NC(CC2)=O)=O)CC3=CC(O[C@H]4CN([C@H](CC4)C)CC)=CC=C31
Biological Activity: WIZ degrader 5 (example 41) is a molecular glue degrader for widely interspaced zinc (WIZ) finger motifs with an AC50 of 0.14 nM. WIZ degrader 5 induces the expression of fetal hemoglobin (HbF) with an EC50 of 25 nM. WIZ degrader 5 can be used in research related to hereditary blood disorders, such as sickle cell disease (SCD) and thalassemia[1].
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WIZ degrader 5 | WIZ degrader 5 (example 41) is a molecular glue degrader for widely interspaced zinc (WIZ) finger motifs with an AC50 of 0.14 nM. WIZ degrader 5 induces the expression of fetal hemoglobin (HbF) with an EC50 of 25 nM. WIZ degrader 5 can be used in research related to hereditary blood disorders, such as sickle cell disease (SCD) and thalassemia. | |||||||||||||||||||||
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