2881071-86-7
Chemical Structure
HSP90-IN-10
- CAS No.: 2881071-86-7
- Formula:C30H26FN3O6
- Molecular Weight:543.54
IUPAC Name: (E)-3-fluoro-N-(3-((((3-(4-hydroxy-3-methoxyphenyl)-6,6-dimethyl-6,7-dihydrobenzo[c]isoxazol-4(5H)-ylidene)amino)oxy)carbonyl)phenyl)benzamide
InChIKey: PWRYHQZVUUWECO-PPFNPFNJSA-N
SMILES: COC1=CC(C2=C3C(CC(C)(C/C3=N\OC(C4=CC(NC(C5=CC(F)=CC=C5)=O)=CC=C4)=O)C)=NO2)=CC=C1O
Biological Activity: HSP90-IN-10 (Compound 16s) is a potent inhibitor of HSP90. HSP90-IN-10 exhibits high antiproliferative potency against HCC1954 breast cancer cells with the IC50 value of 6 µM. HSP90-IN-10 does not inhibit the growth of normal epithelial cells. HSP90-IN-10 also induces apoptosis[1].
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HSP90-IN-10 | HSP90-IN-10 (Compound 16s) is a potent inhibitor of HSP90. HSP90-IN-10 exhibits high antiproliferative potency against HCC1954 breast cancer cells with the IC50 value of 6 µM. HSP90-IN-10 does not inhibit the growth of normal epithelial cells. HSP90-IN-10 also induces apoptosis. | |||||||||||||||||||||
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Keywords
