2882097-31-4
2882097-31-4
Chemical Structure
STING agonist-43
- CAS No.: 2882097-31-4
- Formula:C21H23NO4
- Molecular Weight:353.41
SMILES: O=C1C2=C(N(C3=C(C(C)=C(C=C31)OC)C)CC(OCC)=O)C=CC(C)=C2
Biological Activity: STING agonist-43 (Compound 67) is a selective STING agonist (EC50: 20.53 μM). STING agonist-43 selectively amplifies cGAMP-dependent STING pathway activation by modulating STING oligomerization. B16.F10 has antitumor activity in a mouse melanoma model. STING agonist-43 can be used for the study of cancer immunity[1].
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STING agonist-43 | STING agonist-43 (Compound 67) is a selective STING agonist (EC50: 20.53 μM). STING agonist-43 selectively amplifies cGAMP-dependent STING pathway activation by modulating STING oligomerization. B16.F10 has antitumor activity in a mouse melanoma model. STING agonist-43 can be used for the study of cancer immunity. | |||||||||||||||||||||
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