2890814-94-3
2890814-94-3
Chemical Structure
FAK inhibitor 7
- CAS No.: 2890814-94-3
- Formula:C32H37N7O3
- Molecular Weight:567.68
InChIKey: KKHBSCMQOBAAKX-UHFFFAOYSA-N
SMILES: O=C1CCC2=C1C(OC3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5OC)=N3)=CC=C2
Biological Activity:
FAK inhibitor 7 is a type of FAK inhibitor with an IC50 value of 3.58 nM. FAK inhibitor 7 can inhibit the downstream signaling cascades of FAK (like Src and AKT), causing ovarian cancer cells to stall in the G0/G1 phase and induce cytotoxic autophagy. FAK inhibitor 7 can also suppress tumor metastasis and growth in ovarian cancer mice[1].
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FAK inhibitor 7 | FAK inhibitor 7 is a type of FAK inhibitor with an IC50 value of 3.58 nM. FAK inhibitor 7 can inhibit the downstream signaling cascades of FAK (like Src and AKT), causing ovarian cancer cells to stall in the G0/G1 phase and induce cytotoxic autophagy. FAK inhibitor 7 can also suppress tumor metastasis and growth in ovarian cancer mice. |
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References
Keywords
