2902679-53-0
2902679-53-0
Chemical Structure
AR antagonist 5
- CAS No.: 2902679-53-0
- Formula:C23H21F3N6O2
- Molecular Weight:470.45
InChIKey: OUFWUTDTAQRRHQ-IRZJEQJZSA-N
SMILES: C[C@](CN1CC2CC(N2C3=CC=C(C=C3)C#N)C1)(C(NC4=CN=C(C(C(F)(F)F)=C4)C#N)=O)O
Biological Activity: AR antagonist 5 (compound 30a) is a selective androgen receptor (AR) antagonist with an IC50 value of 134.8 nM. AR antagonist 5 has favorable pharmacokinetic properties and shows a high skin exposure and low plasma exposure[1.
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AR antagonist 5 | AR antagonist 5 (compound 30a) is a selective androgen receptor (AR) antagonist with an IC50 value of 134.8 nM. AR antagonist 5 has favorable pharmacokinetic properties and shows a high skin exposure and low plasma exposure[1. | |||||||||||||||||||||
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