29065-05-2
Chemical Structure
Hexanorcucurbitacin D
- CAS. Nr.: 29065-05-2
- Formula:C24H34O5
- Molecular Weight:402.52
IUPAC Name: (2S,8S,9R,10R,13R,14S,16R,17R)-17-acetyl-2,16-dihydroxy-4,4,9,13,14-pentamethyl-1,4,7,8,9,10,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-3,11(2H)-dione
InChIKey: DBGQLXXAKKEGFX-KFUQAJKQSA-N
SMILES: CC([C@H]1[C@@H](C[C@]2([C@@H]3CC=C4[C@H]([C@@]3(C(C[C@]12C)=O)C)C[C@@H](C(C4(C)C)=O)O)C)O)=O
Biological Activity: Hexanorcucurbitacin D, a cucurbitacin, is a weak ecdysteroid receptor agonist. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD)[1][2].
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Hexanorcucurbitacin D | Hexanorcucurbitacin D, a cucurbitacin, is a weak ecdysteroid receptor agonist. Hexanorcucurbitacin D can be isolated from Trichosanthes cucumeroides roots. Hexanorcucurbitacin D can be used for the research of cardiovascular disease (CVD). | |||||||||||||||||||||
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- [1]. Xianjing Zhang, et al. Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives. J Nat Prod. 2020 Dec 24;83(12):3536-3544. [Content Brief]
- [2]. L Dinan, et al. Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor. Biochem J. 1997 Nov 1;327 ( Pt 3)(Pt 3):643-50. [Content Brief]
Keywords
