2907659-86-1
Chemical Structure
BPDA2
- CAS. Nr.: 2907659-86-1
- Formula:C24H30O5
- Molecular Weight:398.49
IUPAC Name: 4'-(carboxymethyl)-4-(nonyloxy)-[1,1'-biphenyl]-3-carboxylic acid
InChIKey: ZNUFCVFEZWEKRQ-UHFFFAOYSA-N
SMILES: CCCCCCCCCOC1=CC=C(C=C1C(O)=O)C2=CC=C(C=C2)CC(O)=O
Biological Activity: BPDA2 is a highly selective and competitive active site SHP2 inhibitor with IC50s of 92.0 nM, 33.39 μM, 40.71 μM for SHP2, SHP1, SHP1B, respectively. DBDA2 downregulates mitogenic and cell survival signaling and RTK expression. BPDA2 suppresses SHP2 mediated signaling and breast cancer cell phenotypes[1].
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BPDA2 | 99.30% | BPDA2 is a highly selective and competitive active site SHP2 inhibitor with IC50s of 92.0 nM, 33.39 μM, 40.71 μM for SHP2, SHP1, SHP1B, respectively. DBDA2 downregulates mitogenic and cell survival signaling and RTK expression. BPDA2 suppresses SHP2 mediated signaling and breast cancer cell phenotypes. | ||||||||||||||||||||
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