2923009-50-9
Chemical Structure
GSK_WRN3
- CAS No.: 2923009-50-9
- Formula:C16H20N2O5S
- Molecular Weight:352.41
InChIKey: NVIXFLSBGMVBNO-LLVKDONJSA-N
SMILES: OC1=C(NC(C(C(N[C@H]2CS(C=C2)(=O)=O)=O)=C1)=O)C3CCCCC3
Biological Activity: GSK_WRN3 is selective WRN helicase inhibitor (pIC50 = 8.6). SK_WRN3 can selectively inhibit the growth of microsatellite unstable (MSI) cancer cells, induce DNA damage, and cause cell cycle arrest. GSK_WRN3 has anti-tumor activity[1].
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GSK_WRN3 | 98.10% | GSK_WRN3 is selective WRN helicase inhibitor (pIC50 = 8.6). SK_WRN3 can selectively inhibit the growth of microsatellite unstable (MSI) cancer cells, induce DNA damage, and cause cell cycle arrest. GSK_WRN3 has anti-tumor activity. | ||||||||||||||||||||
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Keywords