2923009-50-9
2923009-50-9
Chemical Structure
GSK_WRN3
- CAS No.: 2923009-50-9
- Formula:C16H20N2O5S
- Molecular Weight:352.41
InChIKey: NVIXFLSBGMVBNO-LLVKDONJSA-N
SMILES: OC1=C(NC(C(C(N[C@H]2CS(C=C2)(=O)=O)=O)=C1)=O)C3CCCCC3
Biological Activity: GSK_WRN3 is selective WRN helicase inhibitor (pIC50 = 8.6). SK_WRN3 can selectively inhibit the growth of microsatellite unstable (MSI) cancer cells, induce DNA damage, and cause cell cycle arrest. GSK_WRN3 has anti-tumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK_WRN3 | 98.10% | GSK_WRN3 is selective WRN helicase inhibitor (pIC50 = 8.6). SK_WRN3 can selectively inhibit the growth of microsatellite unstable (MSI) cancer cells, induce DNA damage, and cause cell cycle arrest. GSK_WRN3 has anti-tumor activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 1.00
HY-164852WRN inhibitor 13 -
Similarity Score 0.83
HY-163942GSK_WRN4 -
Similarity Score 0.83
HY-179326WRN-IN-23 -
Similarity Score 0.65
HY-156580WRN inhibitor 4 -
Similarity Score 0.60
HY-153692WRN inhibitor 1 -
Similarity Score 0.56
HY-153973WRN inhibitor 2 -
Similarity Score 0.52
HY-156579WRN inhibitor 3 -
Similarity Score 0.49
HY-156581WRN inhibitor 5 -
Similarity Score 0.49
HY-183552mCPX -
Explore the MedChemAI to find more analogs
