2924-46-1
2924-46-1
Chemical Structure
Haloperidide
Synonym(s): R3201
- CAS No.: 2924-46-1
- Formula:C26H30ClFN2O2
- Molecular Weight:456.98
IUPAC Name: 4-(4-(3-chlorophenyl)-4-(pyrrolidine-1-carbonyl)piperidin-1-yl)-1-(4-fluorophenyl)butan-1-one
InChIKey: KCDNYRPDKSGQCM-UHFFFAOYSA-N
SMILES: O=C(C1(CCN(CC1)CCCC(C2=CC=C(C=C2)F)=O)C3=CC=CC(Cl)=C3)N4CCCC4
Biological Activity: Haloperidide (R3201) is a neuroleptic compound. Haloperidide is a potent and selective anti-emetic agent. Haloperidide antagonizes Apomorphine (HY-12723)-induced emesis in dogs[1][2].
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Haloperidide | Haloperidide (R3201) is a neuroleptic compound. Haloperidide is a potent and selective anti-emetic agent. Haloperidide antagonizes Apomorphine (HY-12723)-induced emesis in dogs. | |||||||||||||||||||||
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References
- [1]. JANSSEN PA, et al. Haloperidide (R 3201), a highly potent and selective anti-emetic agent in dogs. Nature. 1961 Jun 3;190:911-2. [Content Brief]
- [2]. NIEMEGEERS CJ, et al. Influence of haloperidol (R 1625) and of haloperidide (R 3201) on avoidance and escape behavior of trained dogs in a "jumping box". J Pharm Pharmacol. 1960 Dec;12:744-53. [Content Brief]
