2925307-53-3
2925307-53-3
Chemical Structure
Antifungal agent 68
- CAS No.: 2925307-53-3
- Formula:C23H27ClN2O3
- Molecular Weight:414.93
InChIKey: ZNVPLDJFKLZZOC-UHFFFAOYSA-N
SMILES: CCCC1=CC=C(OCC(OCC2=CC=C(Cl)C=C2)CN3C=CN=C3)C(OC)=C1
Biological Activity: Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51[1].
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Antifungal agent 68 | Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51. | |||||||||||||||||||||
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