299-86-5
Chemical Structure
Crufomate
- CAS No.: 299-86-5
- Formula:C12H19ClNO3P
- Molecular Weight:291.71
IUPAC Name: 4-(tert-butyl)-2-chlorophenyl methyl methylphosphoramidate
InChIKey: BOFHKBLZOYVHSI-UHFFFAOYSA-N
SMILES: O=P(OC)(NC)OC1=CC=C(C(C)(C)C)C=C1Cl
Biological Activity: Crufomate is an organophosphate insecticide. Crufomate is used to control warble fly maggot infections and botfly infestations in dairy cows, and accumulates in milk fat. Crufomate reduces mating responses, conception rates, pup survival rates, and post-weaning body weights of offspring in mice. Crufomate is used in studies related to botfly infestations and gastrointestinal parasitic infections[1][2][3].
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Crufomate | Crufomate is an organophosphate insecticide. Crufomate is used to control warble fly maggot infections and botfly infestations in dairy cows, and accumulates in milk fat. Crufomate reduces mating responses, conception rates, pup survival rates, and post-weaning body weights of offspring in mice. Crufomate is used in studies related to botfly infestations and gastrointestinal parasitic infections. | |||||||||||||||||||||
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- [1]. Khan MA, et al. Reproduction in mice treated with crufomate: effects of dermal treatments on female mice and on their progeny. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1978;13(3):169-81. [Content Brief]
- [2]. O'Keeffe M, et al. Crufomate residues in milk and milk products following treatment of dairy cows for warble-fly. Journal of the Science of Food and Agriculture, 1982, 33(4): 355-360.
- [3]. Poole J B, et al. Anthelmintic efficacy of topically applied crufomate against gastrointestinal parasites in cattle. American Journal of Veterinary Research, 1972, 33(5): 1063.
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