2990619-92-4
Chemical Structure
MtTMPK-IN-8
- CAS No.: 2990619-92-4
- Formula:C24H24N6O7
- Molecular Weight:508.48
IUPAC Name: N-(4-(4-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)piperidin-1-yl)benzyl)-3,5-dinitrobenzamide
InChIKey: ZDMGZOOCIIYGOI-UHFFFAOYSA-N
SMILES: CC1=CN(C(NC1=O)=O)C2CCN(CC2)C3=CC=C(C=C3)CNC(C4=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C4)=O
Biological Activity: MtTMPK-IN-8 (compound 27) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor. MtTMPK-IN-8 has sub-micromolar activity against mycobacteria (MICs = 0.78~9.4 μM) without significant cytotoxicity. MtTMPK-IN-8 can be used for researching tuberculosis[1].
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MtTMPK-IN-8 | MtTMPK-IN-8 (compound 27) is a moderate M. tuberculosis thymidylate kinase (MtbTMPK) inhibitor. MtTMPK-IN-8 has sub-micromolar activity against mycobacteria (MICs = 0.78~9.4 μM) without significant cytotoxicity. MtTMPK-IN-8 can be used for researching tuberculosis. | |||||||||||||||||||||
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Keywords
