2994191-89-6
2994191-89-6
Chemical Structure
PROTAC CDK9 degrader-8
- CAS No.: 2994191-89-6
- Formula:C44H52Cl2N10O7
- Molecular Weight:903.85
InChIKey: GTZWSBFFANSWHT-UHFFFAOYSA-N
SMILES: O=C(C1=NNC=C1NC(C2=C(Cl)C=CC=C2Cl)=O)NC3CCN(CCCCCCCCCCC4=CN(CCCOC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)N=N4)CC3
Biological Activity: PROTAC CDK9 degrader-8 is a CDK9 PROTAC degrader that recruits cereblon. PROTAC CDK9 degrader-8 inhibits the growth of acute myeloid leukemia cells by inducing the degradation of CDK9 protein. PROTAC CDK9 degrader-8 can be used in studies related to CDK9-targeted degradation and acute myeloid leukemia[1].
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PROTAC CDK9 degrader-8 | PROTAC CDK9 degrader-8 is a CDK9 PROTAC degrader that recruits cereblon. PROTAC CDK9 degrader-8 inhibits the growth of acute myeloid leukemia cells by inducing the degradation of CDK9 protein. PROTAC CDK9 degrader-8 can be used in studies related to CDK9-targeted degradation and acute myeloid leukemia. | |||||||||||||||||||||
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