299443-19-9
299443-19-9
Chemical Structure
P0064
- CAS No.: 299443-19-9
- Formula:C15H10N4O5
- Molecular Weight:326.26
IUPAC Name: (Z)-2-hydroxy-N'-(5-nitro-2-oxoindolin-3-ylidene)benzohydrazide
InChIKey: APHAFNNKYPXOOT-UHFFFAOYSA-N
SMILES: O=C(C1=C(O)C=CC=C1)N/N=C(C2=C(N3)C=CC([N+]([O-])=O)=C2)\C3=O
Biological Activity: P0064 is a selective inhibitor targeting the PR domain of PRDM16. P0064 selectively reduces proliferation and survival of FLT3-ITD+ leukemia cells and induces cell apoptosis. P0064 is promising for research of acute myeloid leukemia (AML)[1].
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P0064 | 98.0% | P0064 is a selective inhibitor targeting the PR domain of PRDM16. P0064 selectively reduces proliferation and survival of FLT3-ITD+ leukemia cells and induces cell apoptosis. P0064 is promising for research of acute myeloid leukemia (AML). | ||||||||||||||||||||
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References
Keywords
