301305-73-7
301305-73-7
Chemical Structure
TCS 359
- CAS. Nr.: 301305-73-7
- Formula:C18H20N2O4S
- Molecular Weight:360.43
IUPAC Name: 2-(3,4-dimethoxybenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
InChIKey: FSPQCTGGIANIJZ-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(C2=CC=C(OC)C(OC)=C2)=O)SC3=C1CCCC3)N
Biological Activity: TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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TCS 359 | 99.76% | TCS 359, a 2-acylaminothiophene-3-carboxamide, is a potent and selective FLT3 inhibitor with an IC50 of 42 nM. TCS 359 inhibits MV4-11 cell proliferation with an IC50 of 340 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.70
HY-167710CRCD2 -
Similarity Score 0.69
HY-148036FLT3-IN-16 -
Similarity Score 0.64
HY-124789RTBT1 (Standard) -
Similarity Score 0.61
HY-153008BCR-ABL-IN-7 -
Similarity Score 0.60
HY-146321ANO1-IN-2 -
Similarity Score 0.59
HY-14987AX20017 -
Similarity Score 0.58
HY-47597Protein kinase G inhibitor-2 -
Similarity Score 0.58
HY-180539JT71 -
Similarity Score 0.57
HY-162490TF-S14 -
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